Volume 8 Supplement 1
Vasculitis masquerading as drug allergy: thinking outside the ‘adult’ box of possible diagnoses
© Sarre-Annweiler et al; licensee BioMed Central Ltd. 2012
Published: 2 November 2012
Skin exanthems have a broad differential diagnosis. Henoch-Schonlein-Purpura (HSP) is a small vessel vasculitis with purpura, arthritis, and gastrointestinal symptoms with 90% of cases occurring in children. A dermatology referral was made and the current working diagnosis is HSP or polyarteritis nodosum (PAN) pending a repeat biopsy during the next acute flare. Skin exanthems are often attributed to concurrent medications. The clinical history in a drug allergy assessment is key in distinguishing hypersensitivity drug reactions from other causes including vasculitis. Drug allergy assessment can prevent unnecessary future antimicrobial avoidance in patients with skin exanthems.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.