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Table 1 Descriptive characteristics of study cohort

From: Adrenal suppression in children treated with swallowed fluticasone and oral viscous budesonide for eosinophilic esophagitis

Characteristic

 

Total number of patients analyzed

29

Female, N (%)

7 (24.1)

Median age (y) at diagnosis with EoE (IQR)

13.2 (6.4)

Median age (y) at study enrollment (IQR)

14.1 (4.6)

Features of GC therapy

 Duration of GC therapy (days ± SD)

104.6 ± 23.7

 Oral viscous budesonide, N (%)

26 (89.7)

 Swallowed fluticasone, N (%)

3 (10.3)

Concomitant conditions, N (%)

 Asthma

21 (72.4)

 Allergiesa

27 (93.1)

 Eczema

10 (34.5)

Additional forms of GC therapy, by patient, N (%)

 Total number of patients receiving additional forms

13 (44.8 %)

 Inhaled corticosteroidsb

11 (37.9 %)

 Intranasal

1 (3.4 %)

 Topical

2 (6.9 %)

  1. EoE eosinophilic esophagitis, ICS inhaled corticosteroids, IQR interquartile range, GC glucocorticoid, N number, SD standard deviation, y years
  2. aA diagnosis of allergy was made based on skin prick testing for food and/or environmental allergies by an allergist
  3. bMost participants had a history of infrequent ICS use during inter-current infection only. Two participants were being actively treated with daily moderate ICS doses (Flovent 250 mcg daily and Alvesco 400 mcg daily)