Rancé F. Animal dander allergy in children. Arch Pédiatrie Organe Off Sociéte Fr Pédiatrie. 2006;13:584–6.
Article
Google Scholar
Heinzerling L, Frew AJ, Bindslev-Jensen C, Bonini S, Bousquet J, Bresciani M, et al. Standard skin prick testing and sensitization to inhalant allergens across Europe—a survey from the GALEN network. Allergy. 2005;60:1287–300.
Article
CAS
PubMed
Google Scholar
Heinzerling LM, Burbach GJ, Edenharter G, Bachert C, Bindslev-Jensen C, Bonini S, et al. GA(2)LEN skin test study I: GA(2)LEN harmonization of skin prick testing: novel sensitization patterns for inhalant allergens in Europe. Allergy. 2009;64:1498–506.
Article
CAS
PubMed
Google Scholar
Anderson MC, Baer H. Allergenically active components of cat allergen extracts. J Immunol. 1981;127:972–5.
CAS
PubMed
Google Scholar
Løwenstein H, Lind P, Weeke B. Identification and clinical significance of allergenic molecules of cat origin. Part of the DAS 76 Study. Allergy. 1985;40:430–41.
Article
PubMed
Google Scholar
Riccio AM, De Ferrari L, Chiappori A, Ledda S, Passalacqua G, Melioli G, et al. Molecular diagnosis and precision medicine in allergy management. Clin Chem Lab Med. 2016;54:1705–14.
Article
CAS
PubMed
Google Scholar
Ohman JL, Lowell FC, Bloch KJ. Allergens of mammalian origin. III. Properties of a major feline allergen. J Immunol Baltim Md 1950. 1974;113:1668–77.
CAS
Google Scholar
Konradsen JR, Fujisawa T, van Hage M, Hedlin G, Hilger C, Kleine-Tebbe J, et al. Allergy to furry animals: new insights, diagnostic approaches, and challenges. J Allergy Clin Immunol. 2015;135:616–25.
Article
PubMed
Google Scholar
Kaiser L, Velickovic TC, Badia-Martinez D, Adedoyin J, Thunberg S, Hallén D, et al. Structural characterization of the tetrameric form of the major cat allergen Fel d 1. J Mol Biol. 2007;370:714–27.
Article
CAS
PubMed
Google Scholar
Duffort O, Carreira J, Lombardero M. Monoclonal antibodies against Fel d I and other clinically relevant cat allergens. Immunol Lett. 1988;17:71–7.
Article
CAS
PubMed
Google Scholar
Morgenstern JP, Griffith IJ, Brauer AW, Rogers BL, Bond JF, Chapman MD, et al. Amino acid sequence of Fel dI, the major allergen of the domestic cat: protein sequence analysis and cDNA cloning. Proc Natl Acad Sci USA. 1991;88:9690–4.
Article
CAS
PubMed
PubMed Central
Google Scholar
Griffith IJ, Craig S, Pollock J, Yu XB, Morgenstern JP, Rogers BL. Expression and genomic structure of the genes encoding FdI, the major allergen from the domestic cat. Gene. 1992;113:263–8.
Article
CAS
PubMed
Google Scholar
Hilger C, Kler S, Arumugam K, Revets D, Muller CP, Charpentier C, et al. Identification and isolation of a Fel d 1-like molecule as a major rabbit allergen. J Allergy Clin Immunol. 2014;133:759–66.
Article
CAS
PubMed
Google Scholar
Seppälä U, Hägglund P, Wurtzen PA, Ipsen H, Thorsted P, Lenhard T, et al. Molecular characterization of major cat allergen Fel d 1: expression of heterodimer by use of a baculovirus expression system. J Biol Chem. 2005;280:3208–16.
Article
PubMed
Google Scholar
Kaiser L, Grönlund H, Sandalova T, Ljunggren H-G, van Hage-Hamsten M, Achour A, et al. The crystal structure of the major cat allergen Fel d 1, a member of the secretoglobin family. J Biol Chem. 2003;278:37730–5.
Article
CAS
PubMed
Google Scholar
Ligabue-Braun R, Sachett LG, Pol-Fachin L, Verli H. The calcium goes meow: effects of ions and glycosylation on Fel d 1, the major cat allergen. PLoS ONE. 2015;10:e0132311.
Article
PubMed
PubMed Central
Google Scholar
Vailes LD, Li Y, Bao Y, DeGroot H, Aalberse RC, Chapman MD. Fine specificity of B-cell epitopes on Felis domesticus allergen I (Fel d I): effect of reduction and alkylation or deglycosylation on Fel d I structure and antibody binding. J Allergy Clin Immunol. 1994;93:22–33.
Article
CAS
PubMed
Google Scholar
Bond JF, Brauer AW, Segal DB, Nault AK, Rogers BL, Kuo MC. Native and recombinant Fel dI as probes into the relationship of allergen structure to human IgE immunoreactivity. Mol Immunol. 1993;30:1529–41.
Article
CAS
PubMed
Google Scholar
Karn RC. The mouse salivary androgen-binding protein (ABP) alpha subunit closely resembles chain 1 of the cat allergen Fel dI. Biochem Genet. 1994;32:271–7.
Article
CAS
PubMed
Google Scholar
Vervloet D, Birnbaum J. Origine des allergènes du chat. Rev Fr Allergol. 1995;35:533–8.
Google Scholar
Charpin C, Mata P, Charpin D, Lavaut MN, Allasia C, Vervloet D. Fel d I allergen distribution in cat fur and skin. J Allergy Clin Immunol. 1991;88:77–82.
Article
CAS
PubMed
Google Scholar
Bartholomé K, Kissler W, Baer H, Kopietz-Schulte E, Wahn U. Where does cat allergen 1 come from? J Allergy Clin Immunol. 1985;76:503–6.
Article
PubMed
Google Scholar
Mata P, Charpin D, Charpin C, Lucciani P, Vervloet D. Fel d I allergen: skin and or saliva? Ann Allergy. 1992;69:321–2.
CAS
PubMed
Google Scholar
Jalil-Colome J, de Andrade AD, Birnbaum J, Casanova D, Mège JL, Lanteaume A, et al. Sex difference in Fel d 1 allergen production. J Allergy Clin Immunol. 1996;98:165–8.
Article
CAS
PubMed
Google Scholar
de Blay F, Krieger P. Les allergies aux principaux mammifères domestiques et leur traitement. Rev Fr Allergol. 1997;37:56–64.
Google Scholar
Wentz PE, Swanson MC, Reed CE. Variability of cat-allergen shedding. J Allergy Clin Immunol. 1990;85:94–8.
Article
CAS
PubMed
Google Scholar
Carayol N, Birnbaum J, Magnan A, Ramadour M, Lanteaume A, Vervloet D, et al. Fel d 1 production in the cat skin varies according to anatomical sites. Allergy. 2000;55:570–3.
Article
CAS
PubMed
Google Scholar
Avner DB, Perzanowski MS, Platts-Mills TA, Woodfolk JA. Evaluation of different techniques for washing cats: quantitation of allergen removed from the cat and the effect on airborne Fel d 1. J Allergy Clin Immunol. 1997;100:307–12.
Article
CAS
PubMed
Google Scholar
Nageotte C, Park M, Havstad S, Zoratti E, Ownby D. Duration of airborne Fel d 1 reduction after cat washing. J Allergy Clin Immunol. 2006;118:521–2.
Article
CAS
PubMed
Google Scholar
Arbes SJ, Cohn RD, Yin M, Muilenberg ML, Friedman W, Zeldin DC. Dog allergen (Can f 1) and cat allergen (Fel d 1) in US homes: results from the National Survey of Lead and Allergens in Housing. J Allergy Clin Immunol. 2004;114:111–7.
Article
PubMed
Google Scholar
Salo PM, Arbes SJ, Crockett PW, Thorne PS, Cohn RD, Zeldin DC. Exposure to multiple indoor allergens in US homes and its relationship to asthma. J Allergy Clin Immunol. 2008;121:678–84.e2.
Article
Google Scholar
Munir A. Allergens in school dust. I. The amount of the major cat (Fel d I) and dog (Can f I) allergens in dust from Swedish schools is high enough to probably cause perennial symptoms in most children with asthma who are sensitized to cat and dog. J Allergy Clin Immunol. 1993;91:1067–74.
Article
CAS
PubMed
Google Scholar
Justino CM, Segundo GRS, Pereira FL, Silva DAO, Sopelete MC, Sung SSJ, et al. Mite and pet allergen exposure in Brazilian private cars. Ann Allergy Asthma Immunol. 2005;94:658–61.
Article
PubMed
Google Scholar
Enberg RN, Shamie SM, McCullough J, Ownby DR. Ubiquitous presence of cat allergen in cat-free buildings: probable dispersal from human clothing. Ann Allergy. 1993;70:471–4.
CAS
PubMed
Google Scholar
Luczynska C. Airborne concentrations and particle size distribution of allergen derived from domestic cats (Felis domesticus). Measurements using cascade impactor, liquid impinger, and a two-site monclonal antibody assay for Fel d I. Am Rev Respir Dis. 1990;141:361–7.
Article
CAS
PubMed
Google Scholar
Lieutier-Colas F. Bronchial challenge tests in patients with asthma sensitized to cats: the importance of large particles in the immediate response. Am J Respir Crit Care Med. 2003;167:1077–82.
Article
PubMed
Google Scholar
Zeidler MR, Goldin JG, Kleerup EC, Kim HJ, Truong DA, Gjertson DW, et al. Small airways response to naturalistic cat allergen exposure in subjects with asthma. J Allergy Clin Immunol. 2006;118:1075–81.
Article
PubMed
Google Scholar
Erwin EA, Woodfolk JA, Custis N, Platts-Mills TAE. Animal danders. Immunol Allergy Clin North Am. 2003;23:469–81.
Article
PubMed
Google Scholar
Platts-Mills TAE. Paradoxical effect of domestic animals on asthma and allergic sensitization. JAMA J Am Med Assoc. 2002;288:1012–4.
Article
Google Scholar
Lau S, Illi S, Platts-Mills TAE, Riposo D, Nickel R, Grüber C, et al. Longitudinal study on the relationship between cat allergen and endotoxin exposure, sensitization, cat-specific IgG and development of asthma in childhood—report of the German Multicentre Allergy Study (MAS 90). Allergy. 2005;60:766–73.
Article
CAS
PubMed
Google Scholar
Hesselmar B, Aberg N, Aberg B, Eriksson B, Björkstén B. Does early exposure to cat or dog protect against later allergy development? Clin Exp Allergy. 1999;29:611–7.
Article
CAS
PubMed
Google Scholar
Dharmage SC, Lodge CL, Matheson MC, Campbell B, Lowe AJ. Exposure to cats: update on risks for sensitization and allergic diseases. Curr Allergy Asthma Rep. 2012;12:413–23.
Article
PubMed
Google Scholar
Collin SM, Granell R, Westgarth C, Murray J, Paul ES, Sterne JAC, et al. Associations of pet ownership with wheezing and lung function in childhood: findings from a UK birth cohort. PLoS ONE. 2015;10:e0127756.
Article
PubMed
PubMed Central
Google Scholar
Collin SM, Granell R, Westgarth C, Murray J, Paul E, Sterne JAC, et al. Pet ownership is associated with increased risk of non-atopic asthma and reduced risk of atopy in childhood: findings from a UK birth cohort. Clin Exp Allergy. 2015;45:200–10.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lødrup Carlsen KC, Roll S, Carlsen K-H, Mowinckel P, Wijga AH, Brunekreef B, et al. Does pet ownership in infancy lead to asthma or allergy at school age? Pooled analysis of individual participant data from 11 European birth cohorts. PLoS ONE. 2012;7:e43214.
Article
PubMed
PubMed Central
Google Scholar
Gabet S, Just J, Couderc R, Seta N, Momas I. Allergic sensitisation in early childhood: patterns and related factors in PARIS birth cohort. Int J Hyg Environ Health. 2016;219:792–800.
Article
PubMed
Google Scholar
Johnson CC, Ownby DR. Allergies and asthma: do atopic disorders result from inadequate immune homeostasis arising from infant gut dysbiosis? Expert Rev Clin Immunol. 2016;12:379–88.
Article
CAS
PubMed
PubMed Central
Google Scholar
Grönlund H, Adédoyin J, Reininger R, Varga EM, Zach M, Fredriksson M, et al. Higher immunoglobulin E antibody levels to recombinant Fel d 1 in cat-allergic children with asthma compared with rhinoconjunctivitis. Clin Exp Allergy. 2008;38:1275–81.
Article
PubMed
Google Scholar
Kleine-Tebbe J, Kleine-Tebbe A, Jeep S, Schou C, Løwenstein H, Kunkel G. Role of the major allergen (Fel d I) in patients sensitized to cat allergens. Int Arch Allergy Immunol. 1993;100:256–62.
Article
CAS
PubMed
Google Scholar
Grönlund H, Saarne T, Gafvelin G, van Hage M. The major cat allergen, Fel d 1, in diagnosis and therapy. Int Arch Allergy Immunol. 2010;151:265–74.
Article
PubMed
Google Scholar
Ohman JL, Lowell FC. IgE antibody to cat allergens in an allergic population. J Allergy Clin Immunol. 1977;60:317–23.
Article
PubMed
Google Scholar
de Groot H, Goei KG, van Swieten P, Aalberse RC. Affinity purification of a major and a minor allergen from dog extract: serologic activity of affinity-purified Can f I and of Can f I-depleted extract. J Allergy Clin Immunol. 1991;87:1056–65.
Article
PubMed
Google Scholar
Emara M, Royer P-J, Abbas Z, Sewell HF, Mohamed GG, Singh S, et al. Recognition of the major cat allergen Fel d 1 through the cysteine-rich domain of the mannose receptor determines its allergenicity. J Biol Chem. 2011;286:13033–40.
Article
CAS
PubMed
PubMed Central
Google Scholar
Crack LR, Chan HW, McPherson T, Ogg GS. Phenotypic analysis of perennial airborne allergen-specific CD4+ T cells in atopic and non-atopic individuals. Clin Exp Allergy. 2011;41:1555–67.
Article
CAS
PubMed
Google Scholar
Oldfield WLG, Larché M, Kay AB. Effect of T-cell peptides derived from Fel d 1 on allergic reactions and cytokine production in patients sensitive to cats: a randomised controlled trial. Lancet Lond Engl. 2002;360:47–53.
Article
CAS
Google Scholar
Reefer AJ, Carneiro RM, Custis NJ, Platts-Mills TAE, Sung S-SJ, Hammer J, et al. A role for IL-10-mediated HLA-DR7-restricted T cell-dependent events in development of the modified Th2 response to cat allergen. J Immunol Baltim Md 1950. 2004;172:2763–72.
CAS
Google Scholar
Smoldovskaya O, Feyzkhanova G, Arefieva A, Voloshin S, Ivashkina O, Reznikov Y, et al. Allergen extracts and recombinant proteins: comparison of efficiency of in vitro allergy diagnostics using multiplex assay on a biological microchip. Allergy Asthma Clin Immunol. 2016;12:9.
Article
PubMed
PubMed Central
Google Scholar
Asarnoj A, Hamsten C, Wadén K, Lupinek C, Andersson N, Kull I, et al. Sensitization to cat and dog allergen molecules in childhood and prediction of symptoms of cat and dog allergy in adolescence: a BAMSE/MeDALL study. J Allergy Clin Immunol. 2016;137:813–21.e7.
Article
Google Scholar
Eder K, Becker S, San Nicoló M, Berghaus A, Gröger M. Usefulness of component resolved analysis of cat allergy in routine clinical practice. Allergy Asthma Clin Immunol. 2016;12:58.
Article
PubMed
PubMed Central
Google Scholar
Patelis A, Gunnbjornsdottir M, Alving K, Borres MP, Högman M, Janson C, et al. Allergen extract vs. component sensitization and airway inflammation, responsiveness and new-onset respiratory disease. Clin Exp Allergy. 2016;46:730–40.
Article
CAS
PubMed
Google Scholar
Ukleja-Sokołowska N, Gawrońska-Ukleja E, Żbikowska-Gotz M, Socha E, Lis K, Sokołowski Ł, et al. Analysis of feline and canine allergen components in patients sensitized to pets. Allergy Asthma Clin Immunol. 2016;12:61.
Article
PubMed
PubMed Central
Google Scholar
Perzanowski MS, Ronmark E, James HR, Hedman L, Schuyler AJ, Bjerg A, et al. Relevance of specific IgE antibody titer to the prevalence, severity, and persistence of asthma among 19-year-olds in northern Sweden. J Allergy Clin Immunol. 2016;138:1582–90.
Article
CAS
PubMed
PubMed Central
Google Scholar
Konradsen JR, Nordlund B, Onell A, Borres MP, Grönlund H, Hedlin G. Severe childhood asthma and allergy to furry animals: refined assessment using molecular-based allergy diagnostics. Pediatr Allergy Immunol. 2014;25:187–92.
Article
PubMed
Google Scholar
Nordlund B, Konradsen JR, Kull I, Borres MP, Önell A, Hedlin G, et al. IgE antibodies to animal-derived lipocalin, kallikrein and secretoglobin are markers of bronchial inflammation in severe childhood asthma. Allergy. 2012;67:661–9.
Article
CAS
PubMed
Google Scholar
Bjerg A, Winberg A, Berthold M, Mattsson L, Borres MP, Rönmark E. A population-based study of animal component sensitization, asthma, and rhinitis in schoolchildren. Pediatr Allergy Immunol. 2015;26:557–63.
Article
PubMed
Google Scholar
Till SJ, Francis JN, Nouri-Aria K, Durham SR. Mechanisms of immunotherapy. J. Allergy Clin. Immunol. 2004;113:1025–34.
Article
CAS
PubMed
Google Scholar
Schmitz N, Dietmeier K, Bauer M, Maudrich M, Utzinger S, Muntwiler S, et al. Displaying Fel d1 on virus-like particles prevents reactogenicity despite greatly enhanced immunogenicity: a novel therapy for cat allergy. J Exp Med. 2009;206:1941–55.
Article
CAS
PubMed
PubMed Central
Google Scholar
Alvarez-Cuesta E, Berges-Gimeno P, González-Mancebo E, Mancebo EG, Fernández-Caldas E, Cuesta-Herranz J, et al. Sublingual immunotherapy with a standardized cat dander extract: evaluation of efficacy in a double blind placebo controlled study. Allergy. 2007;62:810–7.
Article
CAS
PubMed
Google Scholar
Mellerup MT, Hahn GW, Poulsen LK, Malling H. Safety of allergen-specific immunotherapy. Relation between dosage regimen, allergen extract, disease and systemic side-effects during induction treatment. Clin Exp Allergy. 2000;30:1423–9.
Article
CAS
PubMed
Google Scholar
Saarne T, Kaiser L, Grönlund H, Rasool O, Gafvelin G, van Hage-Hamsten M. Rational design of hypoallergens applied to the major cat allergen Fel d 1. Clin Exp Allergy. 2005;35:657–63.
Article
CAS
PubMed
Google Scholar
Curin M, Weber M, Thalhamer T, Swoboda I, Focke-Tejkl M, Blatt K, et al. Hypoallergenic derivatives of Fel d 1 obtained by rational reassembly for allergy vaccination and tolerance induction. Clin Exp Allergy. 2014;44:882–94.
Article
CAS
PubMed
PubMed Central
Google Scholar
Norman PS, Ohman JL, Long AA, Creticos PS, Gefter MA, Shaked Z, et al. Treatment of cat allergy with T-cell reactive peptides. Am J Respir Crit Care Med. 1996;154:1623–8.
Article
CAS
PubMed
Google Scholar
Larché M. Peptide therapy for allergic diseases: basic mechanisms and new clinical approaches. Pharmacol Ther. 2005;108:353–61.
Article
PubMed
Google Scholar
Oldfield WL, Kay AB, Larché M. Allergen-derived T cell peptide-induced late asthmatic reactions precede the induction of antigen-specific hyporesponsiveness in atopic allergic asthmatic subjects. J Immunol Baltim Md 1950. 2001;167:1734–9.
CAS
Google Scholar
Campbell JD, Buckland KF, McMillan SJ, Kearley J, Oldfield WLG, Stern LJ, et al. Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression. J Exp Med. 2009;206:1535–47.
Article
CAS
PubMed
PubMed Central
Google Scholar
Worm M, Patel D, Creticos PS. Cat peptide antigen desensitisation for treating cat allergic rhinoconjunctivitis. Expert Opin Investig Drugs. 2013;22:1347–57.
Article
CAS
PubMed
Google Scholar
Patel D, Couroux P, Hickey P, Salapatek AM, Laidler P, Larché M, et al. Fel d 1-derived peptide antigen desensitization shows a persistent treatment effect 1 year after the start of dosing: a randomized, placebo-controlled study. J Allergy Clin Immunol. 2013;131:103–9.e1-7.
Google Scholar
Couroux P, Patel D, Armstrong K, Larché M, Hafner RP. Fel d 1-derived synthetic peptide immuno-regulatory epitopes show a long-term treatment effect in cat allergic subjects. Clin Exp Allergy. 2015;45:974–81.
Article
CAS
PubMed
Google Scholar
Hulse KE, Reefer AJ, Engelhard VH, Satinover SM, Patrie JT, Chapman MD, et al. Targeting Fel d 1 to FcgammaRI induces a novel variation of the T(H)2 response in subjects with cat allergy. J Allergy Clin Immunol. 2008;121:756–62.e4.
Article
Google Scholar
Grönlund H, Vrtala S, Wiedermann U, Dekan G, Kraft D, Valenta R, et al. Carbohydrate-based particles: a new adjuvant for allergen-specific immunotherapy. Immunology. 2002;107:523–9.
Article
PubMed
PubMed Central
Google Scholar
Neimert-Andersson T, Thunberg S, Swedin L, Wiedermann U, Jacobsson-Ekman G, Dahlén S-E, et al. Carbohydrate-based particles reduce allergic inflammation in a mouse model for cat allergy. Allergy. 2008;63:518–26.
Article
CAS
PubMed
Google Scholar
Zhu D, Kepley CL, Zhang K, Terada T, Yamada T, Saxon A. A chimeric human-cat fusion protein blocks cat-induced allergy. Nat Med. 2005;11:446–9.
Article
CAS
PubMed
Google Scholar
Luzar J, Molek P, Šilar M, Korošec P, Košnik M, Štrukelj B, et al. Identification and characterization of major cat allergen Fel d 1 mimotopes on filamentous phage carriers. Mol Immunol. 2016;71:176–83.
Article
CAS
PubMed
Google Scholar
Niespodziana K, Focke-Tejkl M, Linhart B, Civaj V, Blatt K, Valent P, et al. A hypoallergenic cat vaccine based on Fel d 1-derived peptides fused to hepatitis B PreS. J Allergy Clin Immunol. 2011;127:1562–70.e6.
Article
Google Scholar
Senti G, Crameri R, Kuster D, Johansen P, Martinez-Gomez JM, Graf N, et al. Intralymphatic immunotherapy for cat allergy induces tolerance after only 3 injections. J Allergy Clin Immunol. 2012;129:1290–6.
Article
CAS
PubMed
Google Scholar
Freiberger SN, Zehnder M, Gafvelin G, Grönlund H, Kündig TM, Johansen P. IgG4 but no IgG1 antibody production after intralymphatic immunotherapy with recombinant MAT-Feld1 in human. Allergy. 2016;71:1366–70.
Article
CAS
PubMed
Google Scholar
Kim ST, Park SH, Lee SM, Lee SP. Allergen-specific intralymphatic immunotherapy in human and animal studies. Asia Pac Allergy. 2017;7:131–7.
Article
PubMed
PubMed Central
Google Scholar
Canonica GW, Cox L, Pawankar R, Baena-Cagnani CE, Blaiss M, Bonini S, et al. Sublingual immunotherapy: world Allergy Organization position paper 2013 update. World Allergy Organ J. 2014;7:6.
Article
PubMed
PubMed Central
Google Scholar
Lee SP, Choi SJ, Joe E, Lee SM, Lee MW, Shim JW, et al. A pilot study of intralymphatic immunotherapy for house dust mite, cat, and dog allergies. Allergy Asthma Immunol Res. 2017;9:272–7.
Article
PubMed
PubMed Central
Google Scholar