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  1. Antagonism of chemoattractant receptor-homologous molecule on T-helper type-2 cells (CRTH2), a G-protein coupled receptor for prostaglandin D2, could be beneficial for treating allergic disorders. We present f...

    Authors: Paul Ratner, Charles P. Andrews, Frank C. Hampel, Bruce Martin, Dale E. Mohar, Denis Bourrelly, Parisa Danaietash, Sara Mangialaio, Jasper Dingemanse, Abdel Hmissi and Jay van Bavel
    Citation: Allergy, Asthma & Clinical Immunology 2017 13:18
    Content type: Research Published on:

  2. It is well-known that lymphocytes play an important role in systemic lupus erythematosus (SLE). T cell immunoreceptor with Ig and immunoreceptor tyrosine-based inhibitory domains (TIGIT) is one of immunosuppre...

    Authors: Qing Luo, Jianqing Ye, Lulu Zeng, Xue Li, Le Fang, Beihua Ju, Zikun Huang and Junming Li
    Citation: Allergy, Asthma & Clinical Immunology 2017 13:15
    Content type: Research Published on:

  3. The use of gene therapy (GT) for the treatment of primary immune deficiencies (PID) including severe combined immune deficiency (SCID) has progressed significantly in the recent years. In particular, long-term...

    Authors: Xiaobai Xu, Chetankumar S. Tailor and Eyal Grunebaum
    Citation: Allergy, Asthma & Clinical Immunology 2017 13:14
    Content type: Review Published on:

  4. Asthma is an increasingly common chronic disease among children, and data point toward a complex mechanism involving genetic, environmental and epigenetic factors. Epigenetic modifications such as DNA hypo- or...

    Authors: L. Montrose, T. J. Ward, E. O. Semmens, Y. H. Cho, B. Brown and C. W. Noonan
    Citation: Allergy, Asthma & Clinical Immunology 2017 13:12
    Content type: Research Published on:

  5. Thymoglobulin® (anti-thymocyte globulin [rabbit]) is a purified pasteurised, gamma immune globulin obtained by immunisation of rabbits with human thymocytes. Anaphylactic allergic reactions to a first injectio...

    Authors: S. Brabant, A. Facon, F. Provôt, M. Labalette, B. Wallaert and C. Chenivesse
    Citation: Allergy, Asthma & Clinical Immunology 2017 13:13
    Content type: Case Report Published on:

  6. As standard drug treatment of allergic rhinitis (AR) is not completely satisfactory, allergen immunotherapy (AIT) represents the only current treatment with the potential to modify the natural history. House d...

    Authors: Giorgio Ciprandi, Valentina Natoli, Paola Puccinelli and Cristoforo Incorvaia
    Citation: Allergy, Asthma & Clinical Immunology 2017 13:11
    Content type: Letter to the editor Published on:

  7. Peanut sensitization does not necessarily indicate clinical peanut allergy, and uncertainty as to whether or not there is true peanut allergy can lead to increased anxiety and decreased quality of life for pat...

    Authors: Elizabeth Simms, Gary Foster, Katherine Arias, Mark Larché, Tosha Freitag, Tina Walker, Susanna Goncharova, Andrea Marrin, Andreas Freitag, Manel Jordana and Susan Waserman
    Citation: Allergy, Asthma & Clinical Immunology 2017 13:10
    Content type: Research Published on:

  8. The prevalence of sensitization varies geographically based on multiple environmental factors including humidity. The aim of this study was to determine the prevalence of atopy in symptomatic adults. More impo...

    Authors: Stacey D. Lok, Beth E. Davis and Donald W. Cockcroft
    Citation: Allergy, Asthma & Clinical Immunology 2017 13:9
    Content type: Research Published on:

  9. We aimed to determine the effect of sampling time during the day on serum periostin levels in adult participants with and without asthma.

    Authors: Rachel Caswell-Smith, Terrianne Cripps, Thom Charles, Alexander Hosking, Meghana Handigol, Cecile Holweg, John Matthews, Mark Holliday, Corentin Maillot, James Fingleton, Mark Weatherall, Richard Beasley and Irene Braithwaite
    Citation: Allergy, Asthma & Clinical Immunology 2017 13:8
    Content type: Research Published on:

  10. The Addendum Guidelines for the Prevention of Peanut Allergy in the United States—Report of the NIAID-Sponsored Expert Panel were developed to build on previous food allergy guidelines after several key studies d...

    Authors: Kyla Jade Hildebrand, Elissa Michele Abrams, Timothy K. Vander Leek, Julia Elizabeth Mainwaring Upton, Douglas P. Mack, Linda Kirste, Christine McCusker and Sandeep Kapur
    Citation: Allergy, Asthma & Clinical Immunology 2017 13:7
    Content type: Letter to the editor Published on:

  12. Shrimp and house dust mite (HDM) allergies are common in Canadians. Often, both of these allergies occur in the same patient. This may be due to homology of tropomyosin or other potentially shared proteins. Th...

    Authors: Lana Rosenfield, Michael William Tsoulis, Kirolos Milio, Meghan Schnittke and Harold Kim
    Citation: Allergy, Asthma & Clinical Immunology 2017 13:5
    Content type: Research Published on:

  13. Hereditary angioedema (HAE) is a rare but serious condition characterized by recurrent spontaneous attacks of angioedema affecting superficial tissues of upper respiratory and gastrointestinal tracts. The pote...

    Authors: Nina Lakhani Jindal, Elaine Harniman, Nieves Prior, Elia Perez-Fernandez, Teresa Caballero and Stephen Betschel
    Citation: Allergy, Asthma & Clinical Immunology 2017 13:4
    Content type: Short report Published on:

  15. Anti-interleukin (IL)-5 monoclonal antibodies as an eosinophil-depleting strategy is well established, with Mepolizumab being the first biologic approved as an adjunct treatment for severe eosinophilic asthma.

    Authors: Manali Mukherjee, Hui Fang Lim, Sruthi Thomas, Douglas Miller, Melanie Kjarsgaard, Bruce Tan, Roma Sehmi, Nader Khalidi and Parameswaran Nair
    Citation: Allergy, Asthma & Clinical Immunology 2017 13:2
    Content type: Case report Published on:

  16. Food allergy is an important public health problem because it affects children and adults, can be severe and even life-threatening, and may be increasing in prevalence. Beginning in 2008, the National Institut...

    Authors: Alkis Togias, Susan F. Cooper, Maria L. Acebal, Amal Assa’ad, James R. Baker, Lisa A. Beck, Julie Block, Carol Byrd-Bredbenner, Edmond S. Chan, Lawrence F. Eichenfield, David M. Fleischer, George J. Fuchs III, Glenn T. Furuta, Matthew J. Greenhawt, Ruchi S. Gupta, Michele Habich…
    Citation: Allergy, Asthma & Clinical Immunology 2017 13:1
    Content type: Position article and guidelines Published on:

  17. Polyethylene glycols (PEGs) or macrogols are polyether compounds and are widely used as additives in pharmaceuticals, cosmetics, and food.

    Authors: Katharina Wylon, Sabine Dölle and Margitta Worm
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:67
    Content type: Case report Published on:

  18. Anaphylactic reactions involving IgE mediated hypersensitivity have been frequently reported for a number of uncommon foods. However, cases of anaphylaxis to over the counter vitamins and oral supplements have...

    Authors: M. R. Voisin and R. Borici-Mazi
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:66
    Content type: Case report Published on:

  19. Authors: Marie-Claire Arrieta, Andrea Arevalos, Leah Stiemsma, Marta E. Chico, Carlos Sandoval, Minglian Jin, Jens Walter, Phil Cooper, Brett Finlay, Emilie Bernatchez, Matthew J. Gold, Anick Langlois, Pascale Blais-Lecours, Caroline Duchaine, David Marsolais, Kelly M. McNagny…
    Citation: Allergy, Asthma & Clinical Immunology 2016 12(Suppl 2):63
    Content type: Meeting abstracts Published on:

    This article is part of a Supplement: Volume 12 Supplement 2

  20. New Zealand is a developed geographically isolated country in the South Pacific with a population of 4.4 million. Genetic diagnosis is the standard of care for most patients with primary immunodeficiency disor...

    Authors: See-Tarn Woon and Rohan Ameratunga
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:65
    Content type: Research Published on:

  22. Primary immunodeficiency (PID) is a heterogeneous group of inheritable genetic disorders with increased susceptibility to infections, autoimmunity, uncontrolled inflammation and malignancy. Timely precise diag...

    Authors: Saba Sheikhbahaei, Roya Sherkat, Dirk Roos, Majid Yaran, Somayeh Najafi and Alireza Emami
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:62
    Content type: Research Published on:

  23. Component resolved allergen diagnosis allows for a precise evaluation of the sensitization profiles of patients sensitized to felines and canines. An accurate interpretation of these results allows better insi...

    Authors: Natalia Ukleja-Sokołowska, Ewa Gawrońska-Ukleja, Magdalena Żbikowska-Gotz, Ewa Socha, Kinga Lis, Łukasz Sokołowski, Andrzej Kuźmiński and Zbigniew Bartuzi
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:61
    Content type: Research Published on:

  24. In patients with chronic obstructive pulmonary disease (COPD), over-activated T-lymphocytes produce pro-inflammatory cytokines and proliferate in situ in the lower airways and pulmonary parenchyma, contributin...

    Authors: Itsuro Kazama and Tsutomu Tamada
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:60
    Content type: Review Published on:

  25. Research suggests that 90% of patients labeled beta-lactam allergic are able to tolerate penicillins following further assessment. This study aims to define and describe the frequency of true beta-lactam aller...

    Authors: Elissa M. Abrams, Andrew Wakeman, Tom V. Gerstner, Richard J. Warrington and Alexander G. Singer
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:59
    Content type: Research Published on:

  26. Cat allergy is of great importance, and its prevalence is increasing worldwide. Cat allergens and house dust mite allergens represent the major indoor allergens; however, they are ubiquitous. Cat sensitization...

    Authors: Katharina Eder, Sven Becker, Marion San Nicoló, Alexander Berghaus and Moritz Gröger
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:58
    Content type: Research Published on:

  28. Immune responses in allergic diseases begin with allergen sensitization, which usually occurs in childhood. Allergen sensitization involves a complex interplay of genetic and environmental factors, and sensiti...

    Authors: Evelyn Xiu Ling Loo, Jordan Zheng Ting Sim, Anne Goh, Oon Hoe Teoh, Yiong Huak Chan, Seang Mei Saw, Kenneth Kwek, Peter D. Gluckman, Keith M. Godfrey, Hugo Van Bever, Yap Seng Chong, Bee Wah Lee, Michael S. Kramer and Lynette Pei-chi Shek
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:56
    Content type: Research Published on:

  29. Allergic rhinitis affects 10–30 % of the global population and this number is likely to increase in the forthcoming years. Moreover, it commonly co-exists with allergic asthma as a chronic allergic respiratory...

    Authors: Agata Schramm, Barbara Jasiewicz-Honkisz, Grzegorz Osmenda, Grzegorz Wilk, Mateusz Siedlinski, Agnieszka Sagan, Pawel T. Matusik, Joanna Maciag, Tomasz Sliwa, Marta Czesnikiewicz-Guzik and Tomasz P. Mikolajczyk
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:55
    Content type: Research Published on:

  30. Cow’s milk allergy is one of the most common food allergies affecting young children. A subset of milk-allergic individuals can eat baked milk without allergic symptoms which is beneficial in terms of prognost...

    Authors: Allison Kwan, Maria Asper, Sasson Lavi, Elana Lavine, David Hummel and Julia E. Upton
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:54
    Content type: Research Published on:

  31. The Environmental Exposure Unit (EEU) in Kingston, Ontario, Canada is a controlled allergen challenge facility (CACF) that has been previously clinically validated for the use of ragweed and grass pollen in cl...

    Authors: Anne K. Ellis, Mena Soliman, Lisa M. Steacy, Daniel E. Adams, Barnaby Hobsbawn and Terry J. B. Walker
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:53
    Content type: Research Published on:

  32. Atopic dermatitis (AD) is a chronic inflammatory disease caused by the complex interaction of genetic, immune and environmental factors. There have many recent discoveries involving the genetic and epigenetic ...

    Authors: Lianghua Bin and Donald Y. M. Leung
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:52
    Content type: Review Published on:

  33. Exposure to traffic-related air pollution (TRAP) has been implicated in asthma development, persistence, and exacerbation. This exposure is highly significant as large segments of the global population resides...

    Authors: Hong Ji, Jocelyn M. Biagini Myers, Eric B. Brandt, Cole Brokamp, Patrick H. Ryan and Gurjit K. Khurana Hershey
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:51
    Content type: Review Published on:

  34. To improve care and control for patients with adult-onset asthma, a better understanding of determinants of their risk and outcomes is important. We investigated how associations between asthma, asthma control...

    Authors: Corinna Koebnick, Heidi Fischer, Matthew F. Daley, Assiamira Ferrara, Michael A. Horberg, Beth Waitzfelder, Deborah Rohm Young and Michael K. Gould
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:50
    Content type: Research Published on:

  35. Adrenal suppression (AS), a glucocorticoid (GC) side effect associated with significant morbidity, is well described related to inhaled corticosteroid therapy for asthma. Swallowed topical glucocorticoid thera...

    Authors: Alexandra Ahmet, Eric I. Benchimol, Ellen B. Goldbloom and Janice L. Barkey
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:49
    Content type: Research Published on:

  36. Epidemiological studies have implicated Asian sand dust (ASD) in the increased prevalence of respiratory disorders, including asthma. It has been observed that fungal elements such as β-glucan can be adsorbed ...

    Authors: Kaori Sadakane, Takamichi Ichinose, Masataka Nishikawa, Hirohisa Takano and Takayuki Shibamoto
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:48
    Content type: Research Published on:

  37. In patients with asthma, the fungus Aspergillus fumigatus can cause allergic bronchopulmonary aspergillosis (ABPA). Familial ABPA is reported, and some genetic factors have been associated with the disease, howev...

    Authors: Nicola L. D. Overton, David W. Denning, Paul Bowyer and Angela Simpson
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:47
    Content type: Research Published on:

  38. Adult onset food allergy is a rare, but increasingly recognized phenomenon. Mast cell activation syndromes present an ongoing diagnostic and classification challenge. The combination of the two has been rarely...

    Authors: Colin Barber and Chrystyna Kalicinsky
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:46
    Content type: Case Report Published on:

  39. Heterogeneity has been noted in the selection and reporting of disease-specific, pediatric outcomes in randomized controlled trials (RCTs). The consequence is invalid results or difficulty comparing results ac...

    Authors: Tamar Rubin, Jacqueline Clayton, Denise Adams, Rabin Persad and Sunita Vohra
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:45
    Content type: Research Published on:

  40. Several studies have reported that oral immunotherapy (OIT) is effective for children with cow’s milk (CM) allergy. These studies reported the efficacy of OIT in terms of desensitization, but did not describe ...

    Authors: Masaya Takahashi, Shoichiro Taniuchi, Kazuhiko Soejima, Yasuko Hatano, Sohsaku Yamanouchi and Kazuanri Kaneko
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:44
    Content type: Research Published on:

    The Erratum to this article has been published in Allergy, Asthma & Clinical Immunology 2016 12:57

  41. A1 Role of fibrocytes in allergic rhinitis

    Authors: Marie-Ève Côté, Marie-Ève Boulay, Sophie Plante, Jamila Chakir, Louis-Philippe Boulet, Hanan Ahmed, Maria-Beatriz Ospina, Kyriaki Sideri, Harissios Vliagoftis, Sara F. Johnson, Roberta L. Woodgate, Guilhem Cros, Pierre Teira, Sonia Cellot, Henrique Bittencourt, Helene Decaluwe…
    Citation: Allergy, Asthma & Clinical Immunology 2016 12(Suppl 1):22
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  44. To assess the relationship between any systemic antibiotic prescription within the first year of life and the presence of an ICD-9-CM diagnosis code for food allergy (FA).

    Authors: Bryan L. Love, Joshua R. Mann, James W. Hardin, Z. Kevin Lu, Christina Cox and David J. Amrol
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:41
    Content type: Research Published on:

  45. Allergic rhinitis (AR) is characterised by burdensome nasal and/or ocular symptoms. This inflammatory disease can be debilitating and thus result in considerable health-related and economic consequences.

    Authors: A. Roger, E. Arcalá Campillo, M. C. Torres, C. Millan, I. Jáuregui, E. Mohedano, S. Liñan, P. Verdu, N. Rubira, M. Santaolalla, P. González, A. Orovitg and E. Villarrubia
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:40
    Content type: Research Published on:

  46. The prevalence of allergies and the incidence of cancer are both increasing worldwide. It has been hypothesized that atopy may affect the risk of some cancers.

    Authors: Renata Kozłowska, Andrzej Bożek and Jerzy Jarząb
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:39
    Content type: Research Published on:

  47. Chronic rhinosinusitis (CRS) is a frequent chronic condition, which has origins in complex interactions between genetic, immunological and microbial factors. The role of auto-immunity in CRS remains unclear, a...

    Authors: Philippe Lefrançois, Hugo Chapdelaine, Benoît Côté and Martin Desrosiers
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:38
    Content type: Review Published on:

  48. Hypersensitivity reaction to certain allergens plays a role in the pathogenesis of inflammatory bowel disease (IBD). This study aims to observe the effect of specific immunotherapy in a group of IBD patients.

    Authors: Min Cai, Lu Zeng, Lin-Jing Li, Li-Hua Mo, Rui-Di Xie, Bai-Sui Feng, Peng-Yuan Zheng, Zhi-Gang Liu, Zhan-Ju Liu and Ping-Chang Yang
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:37
    Content type: Research Published on:

  49. Only one previous study, via telephone call, on the prevalence of self-reported food allergies has been performed in Portugal, in a small sample of adults. The objective of this study was to determine the prev...

    Authors: Carlos Lozoya-Ibáñez, Sara Morgado-Nunes, Alexandra Rodrigues, Cláudia Lobo and Luis Taborda-Barata
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:36
    Content type: Research Published on:

  50. Ara h2 sIgE serum levels improve the diagnostic accuracy for predicting peanut allergy, but the use of Ara h2 purified protein as a skin prick test (SPT), has not been substantially evaluated. The fraction of ...

    Authors: Elizabeth Percival, Rani Bhatia, Kahn Preece, Patrick McElduff, Mark McEvoy, Adam Collison and Joerg Mattes
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:35
    Content type: Research Published on:

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