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  1. Allergy immunotherapy (AIT) is acknowledged to produce beneficial mid- and long-term clinical and immunologic effects and increased quality of life in patients with allergic respiratory diseases (such as aller...

    Authors: Pascal Demoly, Giovanni Passalacqua, Oliver Pfaar, Joaquin Sastre and Ulrich Wahn
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:34
    Content type: Review Published on:

  2. The incidence of allergic diseases is increasing gradually and is a global burden affecting the socio-economic quality of life. Identification of allergens is the first step towards paving the way for therapeu...

    Authors: Kavita Ghosal, Bodhisattwa Saha and Swati Gupta Bhattacharya
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:33
    Content type: Research Published on:

  3. In Canada, intravenous immune globulin (IVIg) products are licensed for six disease indications, however it has been demonstrated that patients with a number of other conditions also benefit from IVIg. Here we...

    Authors: Stephen D. Betschel, Richard J. Warrington and Robert Schellenberg
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:32
    Content type: Review Published on:

  4. Several null-mutations in the FLG gene that produce a decrease or absence of filaggrin in the skin and predispose to atopic dermatitis and ichthyosis vulgaris have been described. The relationship with asthma is ...

    Authors: José Luis Cubero, María Isidoro-García, Nieves Segura, David Benito Pescador, Catalina Sanz, Félix Lorente, Ignacio Dávila and Carlos Colás
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:31
    Content type: Research Published on:

  5. Food allergy is a common clinical problem in adults. Given logistical barriers to conducting food challenges, the use of skin prick test (SPT) and specific IgE (sIgE) are important in establishing the diagnosi...

    Authors: Ling Ling, Maria B. Ospina, Kyriaki Sideri and Harissios Vliagoftis
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:30
    Content type: Research Published on:

  6. Egg specific IgE levels are frequently used in combination with skin-prick tests to guide clinical decisions and to monitor egg allergy evolution in children. We compared both Immulite and ImmunoCAP egg specif...

    Authors: François Graham, Philippe Bégin, Louis Paradis, Jonathan Lacombe-Barrios, Jean Paradis and Anne Des Roches
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:29
    Content type: Letter to the Editor Published on:

  7. Authors: Philippe Bégin, Lisa C. Winterroth, Tina Dominguez, Shruti P. Wilson, Liane Bacal, Anjuli Mehrotra, Bethany Kausch, Anthony Trela, Elisabeth Hoyte, Gerri O’Riordan, Scott Seki, Alanna Blakemore, Margie Woch, Robert G. Hamilton and Kari C. Nadeau
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:28
    Content type: Erratum Published on:

    The original article was published in Allergy, Asthma & Clinical Immunology 2014 10:1

  8. Eosinophilia is not an uncommon clinical finding. However, diagnosis of its cause can be a dilemma once common culprits, namely infection, allergy and reactive causes are excluded. Primary immunodeficiency dis...

    Authors: Behdad Navabi and Julia Elizabeth Mainwaring Upton
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:27
    Content type: Review Published on:

  9. Exposure to ammonium persulfate (AP) has been reported to be the main cause of occupational asthma in hairdressers. The aim of this study is to assess how long the asthmatic response to AP can be induced after...

    Authors: M. J. Cruz, M. Olle-Monge, J. A. Vanoirbeek, A. Assialioui, S. Gomez-Olles and X. Muñoz
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:26
    Content type: Research Published on:

  10. Scratching in infants is considered to be related to early development of eczema. Little is known about the effects of maternal immune markers on scratching among infants. The objective is to compare the risks...

    Authors: Nelís Soto-Ramírez, Keith Boyd, Hongmei Zhang, Venugopal Gangur, Laura Goetzl and Wilfried Karmaus
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:25
    Content type: Research Published on:

  12. Although severe reactions to immunoglobulin preparations have been frequently reported, IgE antibodies against IgA are usually not investigated; and occur predominantly in previously sensitized patients. The p...

    Authors: Asal Gharib, Caroline Caperton and Sudhir Gupta
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:23
    Content type: Case report Published on:

  13. In this study, we assessed whether multisystem reactions to egg and extensively-heated (EH) egg during OFCs were associated with a history of multisystem reactions. Records of children, who underwent OFC to eg...

    Authors: Girish Vitalpur, Ann Esquivel, Kirsten M. Kloepfer, James E. Slaven and Frederick E. Leickly
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:21
    Content type: Letter to the Editor Published on:

  14. Allergic rhinitis is the most common form of allergy worldwide. The accuracy of skin testing for allergic rhinitis is still debated. Our primary objective was to evaluate the diagnostic accuracy of skin-prick ...

    Authors: Immaculate F. Nevis, Karen Binkley and Conrad Kabali
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:20
    Content type: Review Published on:

  15. Being one of the most common nasal diseases, chronic rhinosinusitis (CRS) is subdivided into CRS with nasal polyps (NP) and CRS without nasal polyps (CRSsNP). CRSsNP presents itself with a TH1 milieu and neutroph...

    Authors: Katrin König, Christine Klemens, Mareike Haack, Marion San Nicoló, Sven Becker, Matthias F. Kramer and Moritz Gröger
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:19
    Content type: Research Published on:

  16. To evaluate total and specific E immunoglobulin (IgE) antibody concentrations in underage subjects with respiratory allergic diseases.

    Authors: Geusa Felipa de Barros Bezerra, Denise Maria Costa Haidar, Marcos Antonio Custódio Neto da Silva, Walbert Edson Muniz Filho, Ramon Moura dos Santos, Ivone Garros Rosa, Graça Maria de Castro Viana, Luís Zaror and Maria do Desterro Soares Brandão Nascimento
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:18
    Content type: Research Published on:

  17. Overexpression and enhanced release of vascular endothelial growth factor (VEGF) have been detected in various types of allergic inflammation, including asthma.

    Authors: E. Koczy-Baron, A. Grzanka, J. Jochem, R. Gawlik and A. Kasperska-Zajac
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:17
    Content type: Letter to the Editor Published on:

  18. Bisphenol A (BPA) is useful in many manufacturing processes and is also found in commonly used consumer products. Previous experimental studies have reported that perinatal exposure to BPA promotes the develop...

    Authors: Miao He, Takamichi Ichinose, Seiichi Yoshida, Hirohisa Takano, Masataka Nishikawa, Takayuki Shibamoto and Guifan Sun
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:16
    Content type: Research Published on:

  19. Allergen immunotherapy (AIT) may be prescribed for patients with allergic rhinitis (AR) induced by house dust mites (HDM) whether asthma is present or not. Current guidelines provide insufficient support for t...

    Authors: Pascal Demoly, Anne Broué-Chabbert, François Wessel and Antoine Chartier
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:13
    Content type: Research Published on:

  20. Several genome-wide association studies of primary biliary cirrhosis (PBC) in European and Japanese origins have shown significant association of dozens of genetic loci contributive to the susceptibility of PB...

    Authors: Ping Li, Guanting Lu, Li Wang, Ying Cui, Ziyan Wu, Si Chen, Jing Li, Xiaoting Wen, Haoze Zhang, Shijie Mu, Fengchun Zhang and Yongzhe Li
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:14
    Content type: Research Published on:

  22. Immunological test systems for diagnostics of type I hypersensitivity involve the following types of antigens: whole allergen extracts, individual highly purified proteins and their recombinant analogues. The ...

    Authors: Olga Smoldovskaya, Guzel Feyzkhanova, Alla Arefieva, Sergei Voloshin, Olga Ivashkina, Yuriy Reznikov and Alla Rubina
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:9
    Content type: Research Published on:

  23. Asthma in the elderly is poorly understood as very few studies have included these patients. DNA methylation can affect the expression of asthma susceptibility genes. Methyl groups can be produced through a ch...

    Authors: Michele Columbo and Albert S. Rohr
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:15
    Content type: Short report Published on:

  24. Food allergy is the most common cause of anaphylaxis in children. Intramuscular delivery of epinephrine auto-injectors (EAI) is the standard of care for the treatment of anaphylaxis. We examined if children an...

    Authors: Sten Dreborg, Xia Wen, Laura Kim, Gina Tsai, Immaculate Nevis, Ryan Potts, Jack Chiu, Arunmozhi Dominic and Harold Kim
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:11
    Content type: Research Published on:

    The Erratum to this article has been published in Allergy, Asthma & Clinical Immunology 2017 13:33

  25. T-cell receptor (TCR) repertoire development is an integral part of the adaptive immune response. T-cell activation requires recognition of appropriately processed antigens by the TCR. Development of a diverse...

    Authors: Gassem Gohal, Christine McCusker, Bruce Mazer, Reza Alizadehfar, Duncan Lejtenyi and Moshe Ben-shoshan
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:10
    Content type: Research Published on:

  26. Several proangiogenic molecules have been implicated in the pathogenies of asthmatic inflammation and remodeling. The aim of the study was to compare the concentration of proangiogenic factors in the sera of a...

    Authors: Joanna S. Makowska, Małgorzata Cieślak, Marzanna Jarzębska, Anna Lewandowska-Polak and Marek L. Kowalski
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:8
    Content type: Research Published on:

  27. The prevalence of many phenotypes of food allergy is increasing. Specific gastrointestinal (GI) phenotype of food allergy (GI allergy) is also increasing but it is difficult to know the prevalence because of m...

    Authors: Paloma Poza-Guedes, Yvelise Barrios, Ruperto González-Pérez, Inmaculada Sánchez-Machín, Andres Franco and Víctor Matheu
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:7
    Content type: Short report Published on:

  28. The immunological literature has been redefining clinical phenomena as hypotheses emerge regarding causal links between triggers, immunologic manifestations, and their specific inflammatory cascades. Of late, ...

    Authors: Matthew P. Cheng, Michael G. Kozoriz, Amir A. Ahmadi, John Kelsall, Katryn Paquette and Jake M. Onrot
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:6
    Content type: Case report Published on:

  29. Accumulating evidence indicates a strong correlation between allergic disease and cardiovascular risks. In spite of this, the data concerning the association between allergic rhinitis (AR) and cardiovascular r...

    Authors: In Cheol Hwang, Yong Joo Lee, Hong Yup Ahn and Sang Min Lee
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:5
    Content type: Short report Published on:

  30. Human African trypanosomiasis due to Trypanosoma brucei rhodesiense is invariably fatal if untreated with up to 12.3 million people at a risk of developing the disease in Sub-Saharan Africa. The disease is charac...

    Authors: Charles D. Kato, Enock Matovu, Claire. M. Mugasa, Ann Nanteza and Vincent P. Alibu
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:4
    Content type: Review Published on:

  31. Polyethylene glycol is a ubiquitous, water-soluble, organic compound found in a wide variety of commercially available products. While generally a benign substance, in rare instances, it can induce hypersensit...

    Authors: Baruch D. Jakubovic, Corey Saperia and Gordon L. Sussman
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:3
    Content type: Case report Published on:

  32. The great majority (60–80 %) of patients consulting specialist physicians for allergic respiratory disease are polysensitized and thus may be potentially clinically polyallergic. However, management approaches...

    Authors: Pascal Demoly, Giovanni Passalacqua, Oliver Pfaar, Joaquin Sastre and Ulrich Wahn
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:2
    Content type: Review Published on:

  33. Sensitization to aeroallergens increases the risk of developing asthma or allergic rhinitis. Data on sensitization to airborne allergens in the general population in sub-Saharan Africa are lacking. The aim of ...

    Authors: Bertrand Hugo Mbatchou Ngahane, Diane Noah, Malea Nganda Motto, Yacouba Mapoure Njankouo and Louis Richard Njock
    Citation: Allergy, Asthma & Clinical Immunology 2016 12:1
    Content type: Research Published on:

  34. Previous studies have reported that up to 75 % of milk allergic subjects tolerate heated milk products. However, the food used for heated milk challenge is often prepared in a non-standardized manner by the pa...

    Authors: Sabrine Cherkaoui, Philippe Bégin, Louis Paradis, Jean Paradis and Anne Des Roches
    Citation: Allergy, Asthma & Clinical Immunology 2015 11:39
    Content type: Research Published on:

  35. The human microbiome can be defined as the microorganisms that reside within and on our bodies and how they interact with the environment. Recent research suggests that numerous mutually beneficial interaction...

    Authors: Amund Riiser
    Citation: Allergy, Asthma & Clinical Immunology 2015 11:35
    Content type: Review Published on:

  36. Flare-up of allergic rhinitis has been implicated in worsening neuropsychiatric symptoms such as hyperactivity and anxiety in the general population, mostly supported by epidemiological data. However, it is un...

    Authors: Harumi Jyonouchi
    Citation: Allergy, Asthma & Clinical Immunology 2015 11:38
    Content type: Case report Published on:

  37. Long pentraxin 3 (PTX3) is a novel candidate marker for inflammation in many chronic diseases. As a soluble pattern recognition receptor, PTX3 is involved in amplification of inflammatory reactions and regulat...

    Authors: Jingbo Zhang, Latifa Koussih, Lianyu Shan, Andrew J. Halayko, Ben-Kuen Chen and Abdelilah S. Gounni
    Citation: Allergy, Asthma & Clinical Immunology 2015 11:37
    Content type: Research Published on:

  38. Few population-based studies have assessed the prevalence and the risk factors of non-allergic rhinitis (NAR) in comparison to allergic rhinitis (AR). Moreover, epidemiologic data on rhinitis in the elderly su...

    Authors: Lucia Cazzoletti, Marcello Ferrari, Mario Olivieri, Giuseppe Verlato, Leonardo Antonicelli, Roberto Bono, Lucio Casali, Isa Cerveri, Pierpaolo Marchetti, Pietro Pirina, Andrea Rossi, Simona Villani and Roberto de Marco
    Citation: Allergy, Asthma & Clinical Immunology 2015 11:36
    Content type: Research Published on:

  39. A history of penicillin allergy in patients is common, but only 10–15 % are truly allergic. While the gold standard for diagnosing penicillin allergy is challenge, it is not recommended that this be done witho...

    Authors: Lana Rosenfield, Chrystyna Kalicinsky and Richard Warrington
    Citation: Allergy, Asthma & Clinical Immunology 2015 11:34
    Content type: Research Published on:

  40. Chronic rhinosinusitis with nasal polyps is characterized by local inflammation and is categorized into two subtypes in Japan: eosinophilic chronic rhinosinusitis, and non-eosinophilic chronic rhinosinusitis....

    Authors: Shintaro Baba, Ryoji Kagoya, Kenji Kondo, Maho Suzukawa, Ken Ohta and Tatsuya Yamasoba
    Citation: Allergy, Asthma & Clinical Immunology 2015 11:33
    Content type: Research Published on:

  41. Peanuts contain potent food allergens and the prevalence of allergy is reported to increase, especially in children. Since peanut sensitization may differ between different geographical regions, we wanted to i...

    Authors: Ellen Namork and Berit A. Stensby
    Citation: Allergy, Asthma & Clinical Immunology 2015 11:32
    Content type: Research Published on:

  42. Allergic diseases such as asthma and allergic rhinitis constitute a significant burden of disease among women of childbearing age and those who are pregnant. Adequately managing these conditions is paramount i...

    Authors: Paul Oykhman, Harold L. Kim and Anne K. Ellis
    Citation: Allergy, Asthma & Clinical Immunology 2015 11:31
    Content type: Review Published on:

  43. Many types of shellfish including oysters are sometime cooked before ingestion and it has been demonstrated that cooking may affect the allergenicity of food. Therefore, the aim of our present study is to iden...

    Authors: Zailatul Hani Mohamad Yadzir, Rosmilah Misnan, Faizal Bakhtiar, Noormalin Abdullah and Shahnaz Murad
    Citation: Allergy, Asthma & Clinical Immunology 2015 11:30
    Content type: Research Published on:

  44. Denosumab is a human monoclonal antibody indicated for the treatment of osteoporosis in postmenopausal women with a high risk of fractures. To our knowledge, no cases of desensitization to this drug have been ...

    Authors: D. Gutiérrez-Fernández, María-Jesús Cruz, A. Foncubierta-Fernández, A. Moreno-Ancillo, M. J. Fernández-Anguita, F. Medina-Varo and J. A. Andres-García
    Citation: Allergy, Asthma & Clinical Immunology 2015 11:29
    Content type: Case report Published on:

  45. The knowledge of general practitioner(s) (GPs) regarding food allergy and anaphylaxis and practices in the prescription of epinephrine auto-injector(s) (EAIs) among GPs has previously only been studied using q...

    Authors: Jacquelien Saleh-Langenberg, A. E. J. Dubois, F. Groenhof, J. W. H. Kocks, T. van der Molen and B. M. J. Flokstra-de Blok
    Citation: Allergy, Asthma & Clinical Immunology 2015 11:28
    Content type: Research Published on:

  47. New therapeutic approaches with biologic agents such as anti-cytokine antibodies are currently on trial for the treatment of asthma, rhinosinusitis or allergic diseases necessitating patient selection by bioma...

    Authors: Katrin König, Christine Klemens, Katharina Eder, Marion San Nicoló, Sven Becker, Matthias F. Kramer and Moritz Gröger
    Citation: Allergy, Asthma & Clinical Immunology 2015 11:26
    Content type: Research Published on:

  48. Ethyl-chloride (EC) spray was recently shown to be an effective antipruritic agent, when given 15 min after histamine skin-prick test (SPT), without changing the wheal and flare reaction. We aimed to investiga...

    Authors: Amir Gal-Oz, Shmuel Kivity, Yacov Shacham, Elisheva Fiszer, Ori Rogowsky and Gil Chernin
    Citation: Allergy, Asthma & Clinical Immunology 2015 11:25
    Content type: Research Published on:

  49. The World Allergy Organization estimates that 40 % of the world’s population is affected by allergic diseases. The International Study of Asthma and Allergies in Childhood has completed Phase III and it has no...

    Authors: Magali Herrant, Cheikh Loucoubar, Sabah Boufkhed, Hubert Bassène, Fatoumata Diene Sarr, Laurence Baril, Odile Mercereau-Puijalon, Salaheddine Mécheri, Anavaj Sakuntabhai and Richard Paul
    Citation: Allergy, Asthma & Clinical Immunology 2015 11:24
    Content type: Research Published on:

  50. The purpose of this brief communication is to highlight emerging evidence to existing guidelines regarding potential benefits of supporting early, rather than delayed, peanut introduction during the period of ...

    Authors: David M. Fleischer, Scott Sicherer, Matthew Greenhawt, Dianne Campbell, Edmond S. Chan, Antonella Muraro, Susanne Halken, Yitzhak Katz, Motohiro Ebisawa, Lawrence Eichenfield and Hugh Sampson
    Citation: Allergy, Asthma & Clinical Immunology 2015 11:23
    Content type: Position article and guidelines Published on:

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